Method for producing substituted pyrazoles

Details Method for producing substituted pyrazoles Method for producing substituted pyrazoles

C - Chemistry, Metallurgy

07

D

C07D 231/12 (2006.01)

Patent

CA 2294023

The invention relates to a process for producing pyrazole derivatives of the formula I : (see formula I) where R1 and R2 are, independently of one another, an unsubstituted or substituted C1-C8-alkyl, C3-C8-cycloalkyl, C6-C14-aryl or phenyl-C1-C4-alkyl group, and R1 can also be hydrogen by reaction of carbonyl compounds of the formula lI R1-C(O)-CH(R2)-CH3 with hydrazine, its hydrate or its salts in 30 to 100 wt per ct sulphuric acid in the presence of catalytic quantities of iodine or an iodine compound.

L'invention concerne un procédé de préparation de dérivés de pyrazole par réaction de composés carbonyle R<1>-C(O)-CH(R<2>)-CH2R<3> avec de l'hydrazine, leur hydrate ou leurs sels dans de l'acide sulfurique à 30 à 100 % en poids, en présence de volumes catalytiques d'iode ou d'un composé iodé.

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