Methods for producing .gamma..delta. t cells

Details Methods for producing .gamma..delta. t cells Methods for producing .gamma..delta. t cells

C - Chemistry, Metallurgy

12

N

C12N 5/0783 (2010.01) A61K 35/14 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2475437

The invention concerns a methods for producing lymphocytic cells, as well as tools, reagents and kits useful for implementing same. More particularly, it concerns methods for preparing .gamma..delta. T cells, adapted to industrial production of functional cells of pharmaceutical quality in large amounts. The invention also concerns methods for activating .gamma..delta. T cells, devices adapted to said methods, as well as the resulting cell compositions and their human or animal .gamma..delta. T cells, and can be used in pharmaceutics, therapeutics, experiments, cosmetics, industrial research among others.

La pr~sente demande concerne des m~thodes pour la production de cellules lymphocytaires, ainsi que les outils, r~actifs et kits utilisables pour leur mise en ouvre. Elle concerne plus particuli~rement des m~thodes de pr~paration de lymphocytes .gamma..delta.T, adapt~es ~ une production industrielle de cellules fonctionnelles de qualit~ pharmaceutique et en quantit~s importantes. Elle concerne ~galement des m~thodes d'activation des cellules .gamma..delta.T, des dispositifs adapt~s ~ ces m~thodes, ainsi que les compositions cellulaires obtenues et leurs .gamma..delta.T humaines ou animaux, et peut Útre utilis~e dans les domaines pharmaceutiques, th~rapeutiques, exp~rimentaux, cosm~tiques, de recherche industrielle, etc.

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