Sulfur-containing thyroxane derivatives and their use as...

Details Sulfur-containing thyroxane derivatives and their use as... Sulfur-containing thyroxane derivatives and their use as...

C - Chemistry, Metallurgy

07

C

C07C 323/37 (2006.01) A61K 8/46 (2006.01) A61K 8/49 (2006.01) A61Q 7/00 (2006.01) C07C 317/34 (2006.01) C07C 317/40 (2006.01) C07C 323/41 (2006.01) C07C 323/42 (2006.01) C07D 295/096 (2006.01)

Patent

CA 2375667

The present disclosure describes novel compounds of formula (A), wherein R1- R12, X and Y have the meanings given in the specification and compositions containing them which are particularly useful for treating hair loss in mammals, including arresting and/or reversing hair loss and promoting hair growth. The compounds described herein are cardiac-sparing.

La présente invention concerne de nouveaux composés de la formule (A) dans laquelle R¿1?-R¿12?, X et Y ont les définitions données dans la description, ainsi que des compositions les contenant, lesquels sont particulièrement utiles pour traiter la perte des cheveux chez des mammifères, et permettent notamment de stopper et/ou d'inverser la perte des cheveux et de stimuler leur croissance. Les composés décrits dans l'invention ménagent le coeur.

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