Methods using hydralazine compounds and isosorbide dinitrate...

Details Methods using hydralazine compounds and isosorbide dinitrate... Methods using hydralazine compounds and isosorbide dinitrate...

A - Human Necessities

61

K

A61K 38/00 (2006.01)

Patent

CA 2634473

The invention provides methods for (a) treating decompensated heart failure; (b) treating compensated heart failure; (c) treating renovascular diseases and (d) treating end-stage renal diseases in a patient in need thereof comprising administering an effective amount of (i) at least one hydralazine compound or a pharmaceutically acceptable salt thereof, (ii) isosorbide dinitrate and/or isosorbide mononitrate, and (iii) optionally at least one compound selected from the group consisting of an angiotensin converting enzyme inhibitor, a .beta.-adrenergic antagonist, an angiotensin II antagonist, an aldosterone antagonist, a cardiac glycoside (digitalis) and a diuretic compound or a combination of two or more thereof. The hydralazine compound may be hydralazine hydrochloride.

L'invention concerne des procédés servant à (a) traiter une insuffisance cardiaque décompensée ; (b) traiter une insuffisance cardiaque compensée ; (c) traiter des maladies rénovasculaires ; et (d) traiter des maladies rénales terminales, chez un patient qui en a besoin, en administrant une quantité efficace (i) d'au moins un composé d'hydralazine ou sel acceptable du point de vue pharmaceutique de celui-ci, (ii) de dinitrate d'isosorbide et/ou de mononitrate d'isosorbide et (iii) éventuellement d'au moins un composé sélectionné parmi un inhibiteur de l'enzyme de conversion de l'angiotensine, un antagoniste ß-adrénergique, un antagoniste de l'angiotensine II, un antagoniste de l'aldostérone, un glycoside cardiotonique (digitalique) et un composé diurétique ou une association de deux ou plus de deux de ceux-ci. Le composé d'hydralazine peut être le chlorhydrate d'hydralazine.

Affiliated with

Also associated with

Rating

Methods using hydralazine compounds and isosorbide dinitrate... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods using hydralazine compounds and isosorbide dinitrate..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods using hydralazine compounds and isosorbide dinitrate... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1553532