Transgenic animals having a modified glycoprotein v gene

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/00 (2006.01) A01K 67/027 (2006.01) A61K 49/00 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2337693

The present invention relates to nonhuman transgenic animals in which the GP V gene has been modified. The invention is also useful for identifying agents that modulate the biological functions of GP V, including the screening and identification of potential therapeutic agents.

La présente invention concerne des animaux transgéniques non humains dans lesquels le gène GP V a été modifié. Cette invention permet également d'identifier les agents qui modulent les fonctions biologiques de GP V, notamment par criblage et identification d'agents thérapeutiques potentiels.

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