C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/519 (2006.01) A61P 11/06 (2006.01) A61P 19/08 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01)
Patent
CA 2559196
The invention describes compounds of the general formula (I), a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The said compounds show activity as protein kinase inhibitors, in particular src family tyrosine kinase inhibitors, and may therefore be useful for the treatment of diseases mediated by said tyrosine kinases.
L'invention concerne des composés de formule générale (I), un procédé de fabrication de ceux-ci, des médicaments renfermant ceux-ci et la fabrication de ceux-ci, ainsi que l'utilisation de ces composés comme agents actifs sur le plan pharmaceutique. Les composés présentent une activité comme inhibiteurs de protéine kinases, notamment des inhibiteurs des tyrosine kinases de la famille src, et peuvent être, par conséquent, utiles pour le traitement de maladies induites par des tyrosine kinases.
Honold Konrad
Schaefer Wolfgang
Scheiblich Stefan
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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