C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/10 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 5/103 (2006.01) C07K 5/113 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2149627
Three non-amnestic and non-memory enhancing peptides, Asp Phe Phe Val Gly (SEQ ID NO: 1), Gln Phe Val Gly (SEQ ID NO: 2), and Ala Ile Phe Thr (SEQ ID NO: 3), that block the amnestic effects of .beta.-(12-28), a peptide homologous to amyloid .beta. protein (A.beta.) are disclosed. This invention relates to amelioration of amnesia and other neurotoxicity in Alzheimer disease (AD) caused by deposition of A.beta. and, therefore, relates to attenuation of the disease process and consequential improvement of the quality of life for individuals suffering from AD.
Cette invention se rapporte à trois peptides non amnestiques et n'améliorant pas la mémoire, Asp Phe Phe Val Gly (NO ID SEQ: 1), Gln Phe Val Gly (NO ID SEQ: 2), et Ala Ile Phe Thr (NO ID SEQ: 3), qui bloquent les effets amnestiques du peptide .beta.-(12-28), qui est un peptide homologue à la protéine amyloïde .beta. (A.beta.). Cette invention se rapporte au traitement de l'amnésie et autre neurotoxicité, dans la maladie d'Alzheimer, dues au dépôt de l'A.beta. et se rapporte, par conséquent, à l'atténuation du processus pathologique et à l'amélioration de la qualité de vie chez des individus souffrant de la maladie d'Alzheimer.
City Of Hope
Sim & Mcburney
LandOfFree
Amelioration of amnesia in alzheimer's disease caused by... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Amelioration of amnesia in alzheimer's disease caused by..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amelioration of amnesia in alzheimer's disease caused by... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1554217