Peptidoglycan biosynthetic gene mure from streptococcus...

Details Peptidoglycan biosynthetic gene mure from streptococcus... Peptidoglycan biosynthetic gene mure from streptococcus...

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) C12N 9/00 (2006.01) C12Q 1/25 (2006.01)

Patent

CA 2255989

The invention provides isolated nucleic acid compounds encoding the murE stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the murE enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.

L'invention porte sur des composés d'acide nucléiques isolés codant pour le gène murE biosynthétique du peptide souche du Streptococcus pneumoniae. Elle porte également sur des vecteurs et des cellules hôtes hétérologues transformées exprimant le produit enzymatique murE et sur un procédé d'identification de composés inhibant la biosynthèse des peptides souches.

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