Naphtothiazine positive allosteric ampa receptor modulators...

Details Naphtothiazine positive allosteric ampa receptor modulators... Naphtothiazine positive allosteric ampa receptor modulators...

C - Chemistry, Metallurgy

07

D

C07D 279/02 (2006.01) A61K 31/5415 (2006.01) A61K 31/547 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2449189

The present invention relates to new positive allosteric AMPA-receptor modulators of general formula (I), wherein R1, R2, R3, R4 and R5 may have the meanings given in the specification and claims, processes for preparing them and the use thereof as pharmaceutical compositions.

La présente invention concerne de nouveaux modulateurs allostériques positifs des récepteurs AMPA de formule générale (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ ont les significations indiquées dans la description et dans les revendications, ainsi que des méthodes de préparation desdits modulateurs et leur utilisation sous forme de compositions pharmaceutiques.

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