Gene expression signature for classification of cancers

Details Gene expression signature for classification of cancers Gene expression signature for classification of cancers

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2678919

The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy.

La présente invention concerne un procédé permettant de classer les cancers et les tissus d'origine par analyse des profils d'expression de micro-ARN spécifiques et des molécules d'acides nucléiques leur correspondant. Cette classification selon l'expression basée sur une arborescence de micro-ARN permet d'optimiser le traitement, et de déterminer une thérapie spécifique.

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