Self-excising polynucleotides and uses thereof

Details Self-excising polynucleotides and uses thereof Self-excising polynucleotides and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/82 (2006.01) A01H 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2420316

The present invention includes compositions and methods for providing organisms from which transgenic traits can be easily excised. More specifically, the present invention provides self-excising polynucleotides that contain a desired trait and a recombinase polynucleotide. The present invention provides methods for the elimination of unwanted nucleic acids in agricultural food products. Additionally, the compositions and methods of the present invention provide a means to prevent the escape of certain transgenic traits into the environment.

La présente invention concerne des compositions et des méthodes d'élaboration d'organismes dans lesquels on peut facilement exciser des caractères transgéniques. Plus précisément, l'invention concerne des polynucléotides à auto-excision qui contiennent un caractère souhaité et un polynucléotide recombinase. La présente invention concerne également des méthodes d'élimination des acides nucléiques non souhaités dans les produits alimentaires d'origine agricole. Par ailleurs, les compositions et les méthodes de l'invention permettent de prévenir la fuite de certains caractéristiques dans l'environnement.

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