C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/08 (2006.01) A61K 31/4965 (2006.01) A61K 31/497 (2006.01) A61K 31/551 (2006.01) A61P 9/10 (2006.01) C07D 243/08 (2006.01) C07D 285/36 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 405/14 (2006.01)
Patent
CA 2730056
The invention is concerned with novel heterocyclyl compounds of formula (I), wherein A, X, Y1, Y2, Y3, R3, R4, R5, R6, R7, R8, R9, R10, m, n and p are as defined in the description and m the claims, as well as physiologically acceptable salts thereof These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor and can be used as medica-ments
L'invention porte sur de nouveaux composés hétérocycliques représentés par la formule (I) ; dans laquelle A, X, Y1, Y2, Y3, R3, R4, R5, R6, R7, R8, R9, R10, m, n et p sont tels que définis dans la description et dans les revendications, ainsi que sur des sels physiologiquement acceptables correspondants. Ces composés sont des antagonistes du récepteur CCR2, du récepteur CCR5 et/ou du récepteur CCR3, et peuvent être utilisés en tant que médicaments.
Aebi Johannes
Binggeli Alfred
Green Luke
Hartmann Guido
Maerki Hans P.
F.hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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