Indolylalkylpyridin-2-amines for the inhibition of...

Details Indolylalkylpyridin-2-amines for the inhibition of... Indolylalkylpyridin-2-amines for the inhibition of...

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01)

Patent

CA 2662348

INDOLYLALKYLPYRIDIN-2-AMINES FOR THE INHIBITION OF ß-SECRETASE The present invention provides an indolylalkylpyridin-2-amine compound of formula I CHEMICAL FORMULA SHOULD BE INSERTED HERE AS IT APPEARS ON THE ABSTRACT IN PAPER FORM. The present invention also provides methods for the use thereof to inhibit ß-secretase (BACE) and treat ß-amyloid deposits and neurofibrillary tangles.

La présente invention concerne un composé à base d'une indolylalkylpyridin-2-amine de formule (I). La présente invention concerne également ses procédés d'utilisation pour inhiber la ß-sécrétase (BACE) et traiter des dépôts de ß-amyloïde et des enchevêtrements neurofibrillaires.

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