Compositions and methods useful for hcv infection

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/00 (2006.01) C12N 5/071 (2010.01) C12N 5/078 (2010.01) C12N 7/00 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2441688

The present invention provides compositions comprising cells that can effectively produce HCV after HCV infection, compositions for culturing the cells, methods for making the composition and methods for injecting the cells in the composition with HCV. The present invention also provides methods for assaying HCV production and methods for evaluating compounds that affect the production of HCV.

L'invention concerne des compositions contenant des cellules qui peuvent produire de manière efficace du VHC après infection par le VHC, des compositions pour mettre en culture ces cellules, des méthodes de préparation de ces compositions ainsi que des méthodes d'infection des cellules contenues dans lesdites composition par le VHC. Par ailleurs, l'invention concerne des méthodes d'analyse de la production du VHC ainsi que des méthodes d'évaluation des composés qui affectent la production du VHC.

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