Peptides and/or proteins as well as their use for preparing...

Details Peptides and/or proteins as well as their use for preparing... Peptides and/or proteins as well as their use for preparing...

C - Chemistry, Metallurgy

07

K

C07K 14/75 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/36 (2006.01) C07K 5/083 (2006.01) C07K 5/103 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2430972

The invention relates to peptides or proteins of general formula (I), where R1 and R2 independently = hydrogen, a saturated or unsaturated hydrocarbon group with 1 to 3, in particular up to 10 carbon atoms, Z1 = a histidine or proline group, Z2 = an arginine group, a peptide group or protein group with arginine at the initial terminus, in particular with 2 to 30 amino acids and the salts thereof as well as, for example the amides thereof, or material mixtures thereof and/or with at least one further material. (I) can be used for therapeutic and/or prophylactic applications in human and/or veterinary medicine.

L'invention concerne des peptides ou des protéines de formule générale I (N· ID SEQ 1, 2) (I), dans laquelle R¿1? et R¿2? sont identiques ou différents, signifient hydrogène, un reste hydrocarbure saturé ou insaturé avec 1 à 3, en particulier jusqu'à 10, atomes de carbone, un reste Z¿1?-histidine ou proline, un reste Z¿2?-arginine, un reste peptidique ou un reste protéique avec un reste arginine terminal, notamment avec 2 à 30 acides aminés. Cette invention concerne également les sels desdits peptides ou protéines, tels que des amides, ou des mélanges de substances et/ou au moins une autre substance pour une utilisation thérapeutique et/ou préventive en médecine humaine et/ou vétérinaire.

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