Solid pharmaceutical dispersions with enhanced bioavailability

Details Solid pharmaceutical dispersions with enhanced bioavailability Solid pharmaceutical dispersions with enhanced bioavailability

A - Human Necessities

61

K

A61K 31/495 (2006.01) A61K 9/10 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/17 (2006.01) A61K 31/35 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01)

Patent

CA 2245269

Spray dried solid dispersions comprising a sparingly soluble drug and hydroxypropylmethylcellulose acetate succinate (HPMCAS) provide increased aqueous solubility and/or biavailability in a use environment.

Dispersions solides de type pulvérisation à sec, renfermant un médicament peu soluble et de l'acétate-succinate d'hydroxypropylméthylcellulose (HPMCAS); elles communiquent une hydrosolubilité et (ou) une biodisponibilité plus grandes dans un milieu d'utilisation.

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