Peptide derivative fusion inhibitors of hiv infection

Details Peptide derivative fusion inhibitors of hiv infection Peptide derivative fusion inhibitors of hiv infection

A - Human Necessities

61

K

A61K 39/21 (2006.01) C07K 7/00 (2006.01) C07K 14/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2500248

This invention relates to gp41 peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to gp41 derivatives having inhibiting activity against human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) with enhanced duration of action for the treatment of the respective viral infections.

Cette invention concerne des dérivés de peptides gp41 qui sont des inhibiteurs d'infection virale et/ou possèdent des propriétés antifusogènes. Ladite invention concerne, en particulier, des dérivés de gp41 présentant une activité inhibitrice contre le virus de l'immunodéficience humaine (VIH) et le virus de l'immunodéficience simienne (VIS) avec une durée d'action accrue dans le traitement des infections virales respectives.

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