Indole derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 209/42 (2006.01) A61K 31/395 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2199978

Indole derivatives represented by general formula (I) or pharmacologically acceptable salts thereof, wherein R1 represents hydrogen, lower alkyl, hydroxy, lower alkoxy, halogeno, (a): -O-(CH2)n-OR5 or (b), R2 represents hydrogen, lower alkyl or halogeno; R3 represents hydrogen, lower alkyl or (c) and R4 represents hydroxy, lower alkoxy, optionally substituted aryloxy or - NR10R11, provided that R4 represents -NR10R11 when R3 is hydrogen or lower alkyl.

Dérivés d'indole de formule générale (I), ou sels pharmacologiquement acceptables desdits dérivés, dans laquelle R?1¿ représente hydrogène, alkyle inférieur, hydroxy, alcoxy inférieur, halogéno, la formule (a): -O-(CH¿2?)¿n?-OR?5¿ ou la formule (b), R?2¿ représente hydrogène, alkyle inférieur ou halogéno, R?3¿ représente hydrogène, alkyle inférieur ou la formule (c) et R?4¿ représente hydroxy, alcoxy inférieur, aryloxy éventuellement substitué ou -NR?10¿R?11¿, à condition que R?4¿ représente -NR?10¿R?11¿ lorsque R?3¿ est hydrogène ou alkyle inférieur.

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