Method to predict or monitor the response of a patient to an...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2624613

The invention provides a method for detecting ErbB receptor mutations comprising the steps of providing a bio-fluid sample from a patient; extracting DNA from said sample; and screening said DNA for the presence of one or more mutations that alter tyrosine kinase activity in the receptor.

L'invention a pour objet une méthode pour détecter des mutations du récepteur ErbB qui comprend des étapes consistant à obtenir un échantillon de biofluide d'un patient ; extraire l~ADN dudit échantillon ; et tester ledit ADN pour évaluer la présence d'une ou plusieurs mutations modifiant l'activité de la tyrosine kinase dans le récepteur.

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