Means and methods for the determination of the amount of...

G - Physics – 01 – N

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G01N 33/569 (2006.01)

Patent

CA 2757637

The present invention pertains to the field of tools for ensuring manufacture of polypeptides and quality control. Specifically, it relates to a method for determining of the amount of processed (active) Neurotoxin polypeptide in a solution comprising pro-cessed Neurotoxin polypeptide and partially processed or unprocessed Neurotoxin polypeptide. The present in-vention relates further to a device for determining said amount and a kit adapted to carry out the method of the present invention.

Cette invention concerne le domaine des outils permettant de garantir la fabrication des polypeptides et l'assurance qualité. Plus spécifiquement, elle concerne un procédé permettant de déterminer la quantité de polypeptide neurotoxine remanié (actif) dans une solution comprenant le polypeptide neurotoxine remanié et le polypeptide neurotoxine partiellement remanié ou non remanié. Cette invention concerne, en outre, un dispositif permettant de déterminer ladite quantité et un kit conçu pour mettre en uvre le procédé de la présente invention.

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