Polypeptide of a growth factor receptor family, application...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/15 (2006.01) C07K 14/71 (2006.01) C07K 16/10 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/566 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2094261

Polypeptide of a growth factor receptor family, having a specific sequence and presenting all or part of the following properties: it encourages and/or is involved in the proliferation and/or differenciation of hematopoietic cell lines when obtained from the MPLV retrovirus; it is capable of acting as a hematopoietic growth factor receptor; it is recognized by antibodies directed against it. Polypeptides similar to the above. Applications in the diagnosis of the expression of said ligand polypeptide.

Polypeptide de la famille d'un récepteur de facteur de croissance, de séquence déterminée, possédant toutes ou partie(s) des propriétés suivantes: il favorise et/ou intervient dans la prolifération et/ou la différentiation de lignées cellulaires hématopoïétiques lorsque produit à partir du rétrovirus MPLV; il est susceptible d'intervenir comme récepteur de facteur de croissance hématopoiétique; il est reconnu par des anticorps dirigés contre lui. Polypeptides homologues au précédent. Applications au diagnostic de l'expression de ce polypeptide de ligands.

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