Substituted phenylamidines, pharmaceutical compositions...

Details Substituted phenylamidines, pharmaceutical compositions... Substituted phenylamidines, pharmaceutical compositions...

C - Chemistry, Metallurgy

07

D

C07D 295/15 (2006.01) A61K 31/495 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2397533

The invention relates to phenylamidines of general formula (I), in which R6 and R7 are as defined in claim 1, the tautomers and stereoisomers thereof, including mixtures and salts thereof, in particular, the physiologically acceptable salts with inorganic or organic acids or bases, which display useful pharmacological properties, preferably antithrombotic effects. The invention further relates to medicaments containing said compounds, the use and methods for production thereof.

L'invention concerne des phénylamidines substituées de formule générale (I), dans laquelle R¿6? et R¿7? sont définis dans la revendication 1, leurs tautomères, leurs stéréo-isomères, ainsi que leurs mélanges et leurs sels, notamment leurs sels physiologiquement tolérables, comportant des acides ou des bases inorganiques ou organiques. Ces composés présentent d'intéressantes propriétés pharmacologiques, de préférence des effets antithrombiques. L'invention concerne également des médicaments contenant ces composés, l'utilisation de ces composés et des procédés de préparation de ces derniers.

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