Telaprevir dosing regimen

Details Telaprevir dosing regimen Telaprevir dosing regimen

A - Human Necessities

61

K

A61K 31/497 (2006.01) A61K 31/7056 (2006.01) A61K 38/21 (2006.01) A61K 47/48 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2728248

This invention relates to the use of specific dosing regimens of telaprevir in combination with peg-IFN and RBV in the treatment of HCV patients, wherein the treatment comprises (a) a lead-in phase of administering to the subject pegylated interferon and ribavirin, and (b) a treatment phase of administering to the subject a combination of telaprevir, pegylated interferon and ribavirin.

Cette invention a pour objet lutilisation de schémas posologiques spécifiques du télaprévir en combinaison avec du peg-IFN et de la RBV dans le traitement de patients souffrant du VHC, où le traitement comprend (a) une phase dintroduction consistant à administrer au sujet de linterféron pégylé et de la ribavirine, et (b) une phase de traitement consistant à administrer au sujet une combinaison de télaprévir, dinterféron pégylé et de ribavirine.

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