Oral insulin composition and methods of making and using...

A - Human Necessities – 61 – K

Patent

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A61K 38/28 (2006.01) A61K 9/00 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2518136

A method of lowering blood glucose in a mammal includes orally administering a therapeutically effective amount of crystallized dextran microparticles and insulin to the mammal to lower blood glucose of the mammal. The composition may be a one phase or a structured multi-phase composition for controlled release of insulin.

Selon ce procédé pour faire baisser le niveau de glucose dans le sang d'un mammifère, on administre par voie orale au mammifère une quantité thérapeutiquement efficace de microparticules de dextrane cristallisé et d'insuline afin de faire baisser le niveau de glucose dans le sang du mammifère. La composition peut présenter une seule phase ou une pluralité de phases structurées pour libérer l'insuline de façon contrôlée.

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