Novel polymorph of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/519 (2006.01) A61P 25/00 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01)

Patent

CA 2493359

Polymorph Form III of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-a]- pyrimidin-7-yl}phenyl)acetamide, and use thereof as a sedative-hypnotic, anxiolytic, anticonvulsant, and/or skeletal muscle relaxant agent. Related compositions and methods are also disclosed, particularly with regard to treatment of insomnia.

L'invention concerne la forme polymorphe III de N-méthyl-N-(3-{3-[2-thiénylcarbonyl]-pyrazol-[1,5-a]-pyrimidin-7-yl}phényl)acétamide, et son utilisation en tant qu'agent sédatif hypnotique, anxiolytique, anticonvulsivant, et/ou relaxant les muscles du squelette. L'invention concerne également des compositions et des méthodes associées, en particulier relatives au traitement de l'insomnie.

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