Pharmaceutical combination of bcr-abl and raf inhibitors

Details Pharmaceutical combination of bcr-abl and raf inhibitors Pharmaceutical combination of bcr-abl and raf inhibitors

A - Human Necessities

61

K

A61K 31/506 (2006.01) A61K 31/4725 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2601687

The invention provides a pharmaceutical combination comprising: a) a pyrimidylaminobenzamide compound, and b) a RAF kinase inhibitor and a method for treating or preventing a proliferative disease using such a combination, wherein compound a) has the following general Formula: (I).

La présente invention concerne une combinaison pharmaceutique qui comprend a) un composé de pyrimidylaminobenzamide et b) un inhibiteur de la kinase RAF, ainsi qu~un procédé pour le traitement ou la prévention d'une maladie proliférative en utilisant une telle combinaison, où le composé a) présente la formule générale suivante : (I)

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