Methods for regulating cell mitosis by inhibiting...

A - Human Necessities – 61 – K

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Details

A61K 31/496 (2006.01) A61K 31/34 (2006.01) A61K 31/4525 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61P 35/00 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2730428

Disclosed herein are methods of inhibiting proliferation of a cancer cell or inducing apoptosis of a cancer cell, which does not overexpress N-CoR. Also disclosed herein are methods of inhibiting proliferation or inducing apoptosis of a cancer cell that overexpresses TCTP and methods for determining whether a compound is effective in inducing cell death.

L'invention porte sur des procédés d'inhibition de la prolifération d'une cellule cancéreuse ou d'induction d'une apoptose d'une cellule cancéreuse, qui ne surexprime pas N-CoR. L'invention porte également sur des procédés d'inhibition de la prolifération ou d'induction de l'apoptose d'une cellule cancéreuse qui surexprime la TCTP et sur des procédés permettant de déterminer si un composé est efficace pour induire la mort de cellule.

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