C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61P 1/00 (2006.01) C07H 21/04 (2006.01) C07K 14/195 (2006.01) C07K 14/205 (2006.01) C07K 16/12 (2006.01) C12N 15/11 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2372095
The present invention relates generally to therapeutic compositions for the treatment and/or prophylaxis of intestinal disease conditions in animals and birds caused or exacerbated by Lawsonia intracellularis or similar or otherwise related microorganism. In particular, the present invention provides a novel gene derived from Lawsonia intracellularis which encodes an immunogenic SodC peptide, polypeptide or protein that is particularly useful as an antigen in vaccine preparation for conferring humoral immunity against Lawsonia intracellularis and related pathogens in animal hosts. The present invention is also directed to methods for the treatment and/or prophylaxis of such intestinal disease conditions and to diagnostic agents and procedures for detecting Lawsonia intracellularis or similar or otherwise related microorganisms.
La présente invention porte en général sur des compositions thérapeutiques utilisées dans le traitement et/ou la prophylaxie des maladies intestinales chez les animaux et les oiseaux provoquées ou exacerbées par Lawsonia intracellularis ou similaire ou autre micro-organisme apparenté. Cette invention porte notamment sur un nouveau gène dérivé de Lawsonia intracellularis qui code un peptide, polypeptide ou protéine SodC immunogénique qui est notamment utile comme antigène dans la préparation de vaccins en vue de conférer l'immunité humorale contre Lawsonia intracellularis et des agents pathogènes apparentés chez des animaux hôtes. Cette invention porte également sur des procédés de traitement et/ou prophylaxie de ces maladies intestinales, ainsi que sur des agents diagnostiques et sur des procédures de détection de Lawsonia intracellularis ou similaire ou autres micro-organismes apparentés.
Ankenbauer Robert Gerard
Hasse Detlef
Panaccio Michael
Rosey Everett Lee
Wright Catherine
Agriculture Victoria Services Pty Ltd.
Australian Pork Limited
Pfizer Products Inc.
Smart & Biggar
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