Pharmaceutical compositions comprising quinapril magnesium

Details Pharmaceutical compositions comprising quinapril magnesium Pharmaceutical compositions comprising quinapril magnesium

C - Chemistry, Metallurgy

07

K

C07K 5/062 (2006.01) A61K 38/05 (2006.01) A61P 9/12 (2006.01) C07K 5/065 (2006.01)

Patent

CA 2355347

Stable solid compositions comprising quinapril magnesium can be made using quinapril or an acid addition salt thereof, by reacting the quinapril or acid addition salt with an alkaline magnesium compound in the presence of a solvent, so as to convert all or substantially all of the quinapril or acid addition salt to quinapril magnesium.

On peut préparer des compositions solides stables contenant quinapril magnésium au moyen de quinapril ou d'un de ses sels d'apport acide par réaction de quinapril ou de son sel d'apport acide avec un composé de magnésium alcalin en présence d'un solvant, de façon à convertir la totalité ou pratiquement la totalité du quinapril ou du sel d'apport acide en quinapril magnésium.

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