Novel benzazepines and related heterocyclic derivatives...

Details Novel benzazepines and related heterocyclic derivatives... Novel benzazepines and related heterocyclic derivatives...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) A61K 31/55 (2006.01) C07D 223/16 (2006.01) C07D 243/14 (2006.01) C07D 267/14 (2006.01) C07D 281/10 (2006.01) C07D 285/36 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2431982

The invention relates to novel benzazepines and related heterocyclic derivatives (I) and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.

L'invention concerne de nouvelles benzaz~pines et leurs d~riv~s h~t~rocycliques associ~s (I), ainsi que l'utilisation de celles-ci comme principes actifs dans la pr~paration de compositions pharmaceutiques. L'invention concerne ~galement les aspects aff~rents, notamment les m~thodes de pr~paration de ces compos~s, les compositions pharmaceutiques contenant au moins l'un de ces compos~s, et particuli­rement leur utilisation comme antagoniste du r~cepteur de l'orexine.

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