Crystallization and structure determination of...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/02 (2006.01) C07K 14/31 (2006.01) C12N 9/04 (2006.01) C12N 15/53 (2006.01) G06F 17/50 (2006.01)

Patent

CA 2376065

Staphylococcus aureus elongation factor P S. aureusEF-P has been crystallized, and the three dimensional x-ray crystal structure has been solved to 1.9 .ANG. resolution. The x-ray crystal structure is useful for solving the structure of other molecules or molecular complexes, and designing inhibitors of S. aureusEF-P.

L'invention concerne le facteur P d'élongation du Staphylococcus aureus S. aureusEE-P qui a été cristallisé, et la structure cristalline à rayons X en trois dimensions a été ramenée à une résolution de 1.9 .ANG.. La structure à rayons X sert à réduire la structure d'autres molécules ou complexes moléculaires, et à concevoir des inhibiteurs de S. aureusEF-P.

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