C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 47/48 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 9/36 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2412256
Disclosed herein are nucleic acid sequences that encode G-coupled protein- receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
L'invention concerne des séquences d'acides nucléiques qui codent pour des polypeptides associés aux récepteurs couplés aux protéines G. L'invention concerne aussi des polypeptides codés par ces séquences d'acides nucléiques, ainsi que des anticorps qui se lient de manière immunospécifique au polypeptide, et des dérivés, variantes, mutants ou fragments des polypeptides, polynucléotides, ou anticorps mentionnés. L'invention concerne en outre des procédés thérapeutiques, diagnostiques et de recherche utiles pour le diagnostic, le traitement et la prévention d'affections dans lesquelles interviennent ces acides nucléiques et protéines d'origine humaine.
Gangolli Esha A.
Gerlach Valerie L.
Gusev Vladimir
Herrmann John L.
Macdougall John R.
Curagen Corporation
Ridout & Maybee Llp
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