Simian adenoviruses sadv-36,-42.1, -42.2, and -44 and uses...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 7/00 (2006.01)

Patent

CA 2716928

A recombinant vector comprises simian adenovirus 36, simian adenovirus 42.1, simian adenovirus 42.2 and/or simian adenovirus 44 sequences and a heterologous gene under the con-trol of regulatory sequences. A cell line which expresses one or more simian ade-novirus- 36, -42.1, -42.2 or -44 gene(s) is also described. Methods of using the vec-tors and cell lines are provided.

L'invention porte sur un vecteur recombinant qui comprend des séquences d'adénovirus simien 36, adénovirus simien 42.1, adénovirus simien 42.2 et/ou adénovirus simien 44 et un gène hétérologue sous le contrôle de séquences régulatrices. L'invention porte également sur une lignée cellulaire qui exprime un ou plusieurs gènes d'adénovirus simiens -36, -42.1, -42.2 ou -44. L'invention porte également sur des procédés d'utilisation des vecteurs et des lignées cellulaires.

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