Synthesis of vicinal diamines

C - Chemistry – Metallurgy – 07 – C

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C07C 211/09 (2006.01) C07C 209/66 (2006.01) C07C 211/22 (2006.01)

Patent

CA 2113803

2113803 9303003 PCTABS00019 The present invention relates to an improved method of forming vicinal diamines. The method according to the present invention has the advantage of being highly stereoselective, capable of forming a wide variety of diamines including racemic and enantiomeric forms, and employing readily available starting and reaction materials. In particular the present invention relates to a method of forming vicinal diamines from a bis-imine precursor using nucleophilic additions of organometallic reagents.

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