Human antibody molecules for il-13

Details Human antibody molecules for il-13 Human antibody molecules for il-13

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 11/06 (2006.01) A61P 35/00 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2532799

Specific binding members, in particular human anti-IL-13 antibody molecules and especially those which neutralise IL-13 activity. Methods for using anti- IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, including asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.

L'invention concerne des éléments de liaison spécifiques, en particulier des molécules d'anticorps anti-IL-13, et notamment ceux neutralisant l'activité de l'IL-13. L'invention concerne également des procédés d'utilisation des molécules d'anticorps anti-IL13 pour le diagnostic ou le traitement de troubles associés à l'IL-13, comprenant l'asthme, la dermatite atopique, la rhinite allergique, la fibrose, la maladie intestinale inflammatoire et le lymphome Hodgkinien.

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