Heterocyclic thioesters and ketones

Details Heterocyclic thioesters and ketones Heterocyclic thioesters and ketones

C - Chemistry, Metallurgy

07

D

C07D 207/06 (2006.01) C07D 211/10 (2006.01)

Patent

CA 2602791

This invention relates to neurotrophic low molecular weight, small molecule heterocyclic thioesters and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.

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