Peptides for the detection of hiv-1 group o

Details Peptides for the detection of hiv-1 group o Peptides for the detection of hiv-1 group o

C - Chemistry, Metallurgy

07

K

C07K 14/16 (2006.01) C07K 16/10 (2006.01) C12N 15/49 (2006.01) G01N 33/53 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2676762

This invention relates to peptides and their preparation. The peptides each have a sequence that corresponds to the immunodominant region of the HIV-1 group O gp41 envelope protein. The sequence is characterized in that it does not correspond to any known naturally occurring group O sequence or variant. Furthermore, the peptide binds anti-HIV-1 group O antibodies. There are several uses for the peptides, including the detection of antibodies produced in response to HIV-1 group O infection. The peptides may also be incorporated in mosaics and expressed recombinantly.

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