Detection of neoplasia by analysis of saliva

Details Detection of neoplasia by analysis of saliva Detection of neoplasia by analysis of saliva

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2323060

Methods for detection of a cell proliferative disorder, such as cancer, are provided utilizing analysis of target mutant nucleic acids in saliva specimens are described. The presence of target mutant nucleic acids is indicative of a neoplastic disorder of the lung or the head and neck.

Les procédés de la présente invention portent sur la détection d'une affection à prolifération cellulaire telle que le cancer. On a recours à cet effet à l'analyse d'acides nucléiques mutants cibles contenus dans des prélèvements de salive. La présence de tels acides nucléiques mutants cibles est annonciatrice d'une affection à néoplasie touchant le poumon ou la zone de la tête et du cou.

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