Pharmaceutical composition comprising a combination of...

A - Human Necessities – 61 – K

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A61K 31/18 (2006.01)

Patent

CA 2348882

The invention discloses a safer Antiarrhythmic drug with controlled Beta Adrenergic activity which comprises a combination of dextro- and laevo- rotatory isomers of sotalol as active ingredients in which the range of ratio of said dextro- and laevo- isomer is from 1.5:1 to 3.5:1, pharmaceutical compositions with said combination as active ingredients and its preparation and use of the said combination in the treatment of cardiac ailments in mammals including human being.

L'invention concerne un médicament antiarythmique plus sûr possédant une activité bêta adrénergique, et comprenant une combinaison d'isomères dextrogyres et lévogyres de sotalol en tant que principes actifs, le rapport entre ces isomères dextrogyres et lévogyres étant compris entre 1,5/1 et 3,5/1. L'invention concerne également des compositions pharmaceutiques comprenant cette composition en tant que principe actif, ainsi que des procédés de préparation et d'utilisation de cette combinaison destinée au traitement de troubles cardiaques chez les mammifères, notamment chez l'homme.

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