Analgesic use of n-l-.alpha.-aspartyl-l-phenylalanine...

A - Human Necessities – 61 – K

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A61K 38/05 (2006.01) A23K 1/16 (2006.01) A23K 1/18 (2006.01) A23L 1/236 (2006.01) A61K 38/12 (2006.01)

Patent

CA 2225462

N-L-.alpha.-aspertyl-L-phenylalanine 1-methyl ester and/or its derivatives has been found to have analgesic pain relieving properties in both humans and animals. It has been found to be especially effective in relieving pain associated with osteoarthritis and multiple sclerosis. It can be administered by itself or in combination with other analgesics. When given in combination with other analgesics, N-L-.alpha.-aspartyl-L-phenylalanine 1-methyl ester and/or its derivatives helps to alleviate the detrimental side effects of other analgesic medications by lowering the dosage requirements for pain relief.

On a découvert que le N-L-.alpha.-aspartyl-L-phénylalanine 1-méthyle ester et/ou ses dérivés possédent des propriétés analgésiques pour l'homme et l'animal. Ils se sont avérés particulièrement efficaces pour soulager la douleur associée à l'ostéoarthrite et aux scléroses multiples. On peut les administrer seuls ou combinés à d'autres analgésiques. Combinés à d'autres analgésiques, le N-L-.alpha.-aspartyl-L-phénylalanine 1-méthyle ester et/ou ses dérivés contribuent à atténuer les effets secondaires indésirables d'autres médicaments analgésiques par abaissement du dosage nécessaire au soulagement de la douleur.

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