A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/426 (2006.01) A61K 31/415 (2006.01) A61K 31/4168 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/425 (2006.01)
Patent
CA 2174544
A pharmaceutical composition, useful for treating animals of the mammalian species, including humans, to treat diseases and conditions which normally respond to treatment with alpha2 adrenergic agents, contains as its active alpha2 adrenergic agent ingredient one or more compounds of formula (I) where X is O, S or NH; n is an integer with the values of 0, 1 or 2; when n is 0 then R1 is lower alkyl having 1 to 6 carbon atoms and R2 is H or lower alkyl having 1 to 6 carbon atoms; when n is 1 or 2, then R1 and R2 both are methylene (CH2), or methylene substituted with an R5 group where R5 is lower alkyl of 1 to 6 carbons; R3 and R4 independently are H or lower alkyl having 1 to 6 carbons; R6 is H or lower alkyl of 1 to 6 carbons.
Composition pharmaceutique utile pour traiter des animaux de l'espèce mammifère, y compris les humains, contre des maladies et états pathologiques répondant normalement au traitement par les agents alpha¿2? adrénergiques, qui contient en tant qu'ingrédient actif alpha2 adrénergique un ou plusieurs composés de formule (I) dans laquelle X est O, S ou NH; n est un nombre entier valant 0, 1 ou 2; lorsque n est 0, R¿1? est alkyle inférieur ayant 1 à 6 atomes de carbone et R¿2? est H ou alkyle inférieur ayant 1 à 6 atomes de carbone; lorsque n est 0 ou 1, R¿1? et R¿2? sont tous deux méthylène (CH¿2?) ou méthylène substitué par un groupe R¿5?, R¿5? étant alkyle inférieur doté de 1 à 6 atomes de carbone; R¿3? et R¿4? sont indépendamment H ou alkyle inférieur ayant 1 à 6 atomes de carbone et R¿6? est H ou alkyle inférieur ayant 1 à 6 atomes de carbone.
Burke James E.
Garst Michael E.
Wheeler Larry A.
Allergan
Allergan Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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