Pregesteron antagonists such as cdb-4124 in the treatment of...

A - Human Necessities – 61 – K

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Details

A61K 31/56 (2006.01) A61P 15/00 (2006.01) A61P 15/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2722753

The present invention relates to methods of administering compositions comprising a progesterone receptor antagonist for use in treating estrogen-dependent conditions. The invention is also directed to methods for treating pain associated with endometriosis. The compositions may be administered to females with endometriosis as well as to females undergoing estrogen and/or selective estrogen receptor modulator (SERM) therapy. In certain embodiments, the invention provides a method for suppressing endometrial proliferation.

La présente invention concerne des procédés d'administration de compositions qui comportent un antagoniste du récepteur de la progestérone pour une utilisation dans le traitement d'états dépendant de l'strogène. L'invention concerne également des procédés de traitement de la douleur associée à l'endométriose. Les compositions peuvent être administrées à des femmes présentant une endométriose ainsi qu'à des femmes subissant une thérapie par strogène et/ou modulateur du récepteur d'strogène sélectif (SERM). Dans certains modes de réalisation, l'invention concerne un procédé pour supprimer la prolifération du cancer de lendomètre.

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