Formulation of 5-ht agonists

Details Formulation of 5-ht agonists Formulation of 5-ht agonists

A - Human Necessities

61

K

A61K 31/40 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) A61K 31/405 (2006.01) A61K 31/48 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2260943

This invention comprises a method of treating migraine in a human comprising co-timely administering of a therapeutically effective amount of a 5-HT agonist coordinated with a therapeutically effective amount of an analgesic, particularly a long-acting NSAID, and in some instances, doses below those ordinarily considered as minimum effective doses as to one or both 5-HT agonist and long-acting NSAID. Dosage forms are also included herein.

Cette invention se rapporte à un procédé de traitement de la migraine chez un sujet humain qui consiste à administrer simultanément et à un moment approprié une quantité thérapeutiquement efficace d'un agoniste de 5-hydroxytryptamine (5-HT) et une quantité thérapeutiquement efficace d'un analgésique, notamment un anti-inflammatoire non stéroïdien durable, et dans certains cas, qui consiste à administrer des doses inférieures à celles considérées habituellement comme des doses efficaces minimales, de l'un des composés (ou des deux) que sont l'agoniste de 5-HT et l'anti-inflammatoire non stéroïdien durable. L'invention se rapporte en outre à des formes posologiques contenant lesdits composés.

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