Compositions and methods containing substituted quinolines...

Details Compositions and methods containing substituted quinolines... Compositions and methods containing substituted quinolines...

A - Human Necessities

61

K

A61K 31/10 (2006.01) A61K 6/00 (2006.01) A61K 31/4706 (2006.01) A61K 31/49 (2006.01)

Patent

CA 2514396

Combination therapies of substituted quinolines and substituted diphenyl sulfones are disclosed. More specifically, compositions containing substituted quinolines and substituted diphenyl sulfones are disclosed. In addition, methods of using the compositions in the treatment of neurodegenerative disorders, including, inter alia, Alzheimer's dementia, HIV-1 associated dementia, and Creutzfeld-Jakob disease are also disclosed.

L'invention concerne des traitements combinés à base de quinolines substituées et de diphénylsulfones substitués. D'une manière plus spécifique, l'invention concerne des compositions contenant des quinolines substituées et des diphénylsulfones substitués. L'invention concerne également des méthodes d'utilisation desdites compositions dans le traitement de maladies neurodégénératives, notamment la maladie d'Alzheimer, la démence associée au HIV-1 et la maladie de Creutzfeld-Jakob.

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