A method for detecting human parvovirus antigen

G - Physics – 01 – N

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G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2671474

A method for detecting human parvovirus/erythrovirus antigen in a sample comprises contacting a buffer having a pH in the range 3.0 to 4.0, suitably a citrate/trisodium citrate buffer, with the sample followed by the measurement of the antigen. The measurement of the antigen can be by virus capture enzyme immunoassay. The method is a good indicator of recent infection and can be used in the screening of individual plasma units or pools from which blood products are extracted.

Un procédé de détection d'antigène parvovirus/érythrovirus humain dans un échantillon comprend la mise en contact d'un tampon ayant un pH dans la gamme de 3,0 à 4,0, de façon appropriée un tampon de citrate citrate/trisodium, avec l'échantillon suivi de la mesure de l'antigène. La mesure de l'antigène peut être effectuée par immunoessai enzymatique de capture de virus. Le procédé est un excellent indicateur d'infection récente et peut être utilisé dans le criblage d'unités plasma individuelles ou de pools d'où sont extraits les produits sanguins.

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