Organ perfusion hemoglobins

A - Human Necessities – 01 – N

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A01N 1/02 (2006.01) A61K 35/18 (2006.01)

Patent

CA 2074852

ABSTRACT Novel modified hemoglobin products exhibiting properties rendering them particularly useful for organ perfusion are prepared by reacting hemoglobin with divinyl- sulfone under controlled conditions. The products are substantially free from intramolecular crosslinking and have low oxygen affinities and low viscosities, at the hypothermic temperatures normally used for organ perfusion, e.g. about 15°C.

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