Apparatus and methods of raman spectroscopy for analysis of...

A - Human Necessities – 61 – B

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A61B 5/00 (2006.01) G01N 21/65 (2006.01)

Patent

CA 2216641

The present invention relates to systems of methods of measuring selected analytes in blood and tissue using Raman spectroscopy to aid in diagnosis. More particularly, Raman spectra are collected and analyzed to measure the concentration of dissolved gases and other analytes of interest in blood. Methods include in vivo transdermal and continuous monitoring as well as in vitro blood analysis. Furthermore, a compound parabolic concentrator to increase the amount of detected Raman signal is disclosed.

La présente invention concerne des systèmes et procédés visant à mesurer des analytes du sang et des tissus sélectionnés à l'aide de la spectroscopie Raman à des fins d'aide au diagnostic. Plus précisément, des spectres Raman sont recueillis et analysés afin de mesurer la concentration de gaz dissous et d'autres analytes d'intérêt dans le sang. Lesdits procédés incluent la surveillance transdermique et constante in vivo ainsi que l'analyse du sang in vitro. Est également décrit un miroir composé pour augmenter le volume du signal Raman détecté.

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