The use of 4-phenyl substituted tetrahydroisoquinolines in...

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A61K 31/4738 (2006.01) A61P 13/00 (2006.01) A61P 25/04 (2006.01) A61P 25/06 (2006.01)

Patent

CA 2508311

Provided herein are methods of using compounds of formula (IA, IB, IIA, IIB, IIIA, IIIB) that are aryl- and heteroaryl-substituted tetrahydroisoquinolines, for the treatment of chronic and neuropathic pain, the treatment and prevention of migraine headache, and the treatment of stress, urge and mixed urinary incontinence.

L'invention concerne des méthodes d'utilisation de composés de formule (IA, IB, IIA, IIB, IIIA, IIIB) qui sont des tétrahydroisoquinolines à substitution aryle et hétéroaryle, pour le traitement de la douleur chronique et neuropathique, pour le traitement et la prévention de la migraine, ainsi que pour le traitement du stress, de l'incontinence urinaire impérieuse et mixte.

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