C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/52 (2006.01) A61K 31/403 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 13/00 (2006.01)
Patent
CA 2521788
This invention generally relates to derivatives of substituted azabicyclo hexanes of formula I. The compounds of this invention can function as muscarinic receptor antagonists, and can be used for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to a process for the preparation of the compounds of the present invention, pharmaceutical compositions containing the compounds of the present invention and the methods of treating the diseases mediated through muscarinic receptors.
La présente invention concerne généralement des dérivés d~azabicyclo hexanes substitués répondant à la formule (I). Les composés décrits peuvent jouer le rôle d~antagonistes des récepteurs muscariniques, et peuvent être utilisés pour le traitement de diverses maladies des systèmes respiratoire, urinaire et gastro-intestinal médiées par les récepteurs muscariniques. L~invention concerne d~autre part un procédé pour la préparation desdits composés, des compositions pharmaceutiques les contenant, ainsi que les méthodes pour traiter les maladies médiées par les récepteurs muscariniques.
Gupta Jang Bahadur
Mehta Anita
Silamkoti Arundutt Viswanatham
Dimock Stratton Llp
Ranbaxy Laboratories Limited
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