C - Chemistry – Metallurgy – 12 – M
Patent
C - Chemistry, Metallurgy
12
M
C12M 3/00 (2006.01) C12M 1/00 (2006.01) C12M 1/10 (2006.01) C12M 1/40 (2006.01) C12M 3/02 (2006.01)
Patent
CA 2216467
The present invention comprises a novel culture method and device in which living cells or subcellular biocatalysts are immobilized by the opposition of a centrifugal force field and a liquid flow field. The immobilized cells or biocatalysts are ordered into a three-dimensional array of articles, the density of which is determined by the particle size, shape, intrinsic density and by the selection of combinations of parameters such as liquid flow rate and angular velocity of rotation.
La présente invention concerne un nouveau procédé et un nouveau dispositif de mise en culture selon lesquels des cellules vivantes ou des biocatalyseurs subcellulaires vivants sont maintenus immobiles par l'opposition entre un champ de force centrifuge et un champ de flux de liquide. Les cellules ou les biocatalyseurs maintenus immobiles sont ordonnancés selon une structure tridimensionnelle des article, leur densité étant déterminée par la taille, la forme et la densité intrinsèque des particules et par la sélection de combinaisons de paramètres tels que le débit du liquide, et la vitesse angulaire de rotation.
Finlayson & Singlehurst
Kinetic Biosystems Inc.
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